Features

  • In vitro electrophysiology for diabetes research
  • MEA-based parallelized screening system for intact islets of Langerhans
  • Two configurations for either long-term, incubator-ready chronic or non-invasive acute recordings
Technology

Microelectrode array (MEA) based non-invasive screening

Utilizing the MEA technology allows parallelized recording of beta cell activity of intact islets of Langerhans. Simple handling and higher throughput as in intracellular recordings or patch-clamp comply with academic and industrial needs. As market leader in MEA technology we offer systems for acute and chronic recordings matching your research needs.

Application

Explore new possibilities in drug discovery and diabetes reseach

The MEA technology opens new routes to support the development of new drugs for the treatment of type 2 diabetes mellitus, as well as to elucidate beta cell pathophysiology e.g. during the progression of diabetes. It allows the analysis of isolated human islets, fraction of plateau phase (FOPP) as marker for insulin release, and the investigation of pathophysiological reactions like oxidative stress.

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